Mandrea means: Anyone with “Andrea” as their given name is insulted by “Mandrea”, which is “Mandrea”. Although it may seem like a clever way to insult someone, this is simply a display of his stupidity. The days of insulting another’s gender end when you graduate from third grade. If you’re not nine years old or mentally handicapped, this word must be forgotten. It is, after all, ridiculous. (in Community Dictionary, added by Adelaida Blanco)