What Does It Mean to Say That an Allele is Fixed?

Learn about allele fixation and its implications in population genetics through examples and case studies.

Introduction

Alleles are alternative forms of a gene that can occupy the same position on a chromosome. When we say that an allele is fixed in a population, it means that all individuals in that population have the same allele for a particular gene.

Understanding Fixation

Fixation occurs when a particular allele becomes the only variant present in a population. This can happen through genetic drift, natural selection, or migration. In a fixed population, there is no genetic diversity for that particular gene.

Examples of Fixation

An example of allele fixation can be seen in the case of sickle cell anemia. The allele responsible for sickle cell is fixed in regions where malaria is prevalent because individuals with the sickle cell trait have a survival advantage against malaria.

Another example is the gene responsible for lactose intolerance. In populations where dairy consumption is not prevalent, the allele for lactose intolerance may be fixed due to lack of selection pressure for lactase persistence.

Case Studies

One notable case study of allele fixation is the peppered moth in England. During the Industrial Revolution, the prevalence of dark-colored moths increased due to pollution darkening tree trunks. The allele for dark coloration became fixed as it provided better camouflage against predators.

Implications of Fixation

Allele fixation can have both positive and negative implications. On one hand, fixation can increase the efficiency of natural selection by reducing genetic variation. On the other hand, it can also limit the adaptability of a population in response to changing environments.

Conclusion

In conclusion, the fixation of an allele in a population signifies the uniformity of genetic information for a particular gene. Understanding the process of fixation is crucial in studying population genetics and evolutionary biology.

Leave a Reply

Your email address will not be published. Required fields are marked *