Ed Zachary Disease means: If a person has bad breath that makes their mouth scream “Ed Zachary”, it is referred to as “Ed Zachary”. (in Community Dictionary, added by Kenna Duke)

What else does Ed Zachary Disease mean?

  • If someone’s face is Ed Zachary-like, it means they are Ed Zachary. (in Community Dictionary, added by Catalina Bernard)
  • Ed Zachary Disease refers to when your face is exactly the same as your ass. This means that you’re extremely ugly. (in Community Dictionary, added by Damien Pineda)